RESEARCH REVIEW

Memory Engrams in the Neocortex


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Welcome to the gais Lab

We are interested in everything related to memory and sleep.
How do we learn from new experiences and store memories? What happens to these memories over time?
And what does sleep have to do with this?

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Latest News

February, 1st 2022

We have two open positions for PhD students. We are looking for one psychologist, cognitive scientist, or neuroscientist and one candidate with expertise in Data Science, Machine Learning, Engineering, or related areas. You find all information on PsychJob: here.

November, 12th 2021

Svenja Klinkowski will join the PhD program of the prestigious IMPRS on the Mechanisms of Mental Function and Dysfunction.

October, 10th 2021

Beautiful SWR2 Wissen radio feature on sleep mentation by Eva Wolfangel, featuring amongst others our own work on imaging memory formation in the transition between wake and sleep. Check it out here!

September, 30th 2021

Svenja B sent her regards from the European Sleep Research Society’s Sleep Science School “The Functions of Sleep” currently taking place at the beautiful Villa Clythia in Frèjus, France. She just gave a talk about information processing in the transition to sleep and how we can image the locus coeruleus–noradrenergic system in humans. This fantastic retreat features great lectures by Gabrielle Girardeau, Vlad Vyazovskiy, Iben Lundgaard, Monika Schönauer et al.
 

new comment: Ripples for recall - The hippocampus constructing the context?

September, 1st 2021

Svenja B and Jan Born have published a new comment in Neuron.

DOI

July, 14th 2021

Campus TV Tübingen has interviewed Svenja B on sleep stages and brain activity during dreaming – worth a watch: here!
 

June, 2nd 2020

Svenja B and Monika have organized a symposium at this year’s Psychology and the Brain (PuG) conference. There will be great talks by Niklas Vocke (DZNE Magdeburg), David Berron (Lund University) and Antonia Lenders (Freiburg University).

June, 2nd 2020

Svenja K presents a poster of our new experimental design that disentangles hippocampal and neocortical contributions to memory formation at this year’s Psychology and the Brain (PuG) conference.

June, 1st 2020

Our group has the honour, together with Birgit Derntl and Mannfred Hallschmid, to organize the conference Psychologie und Gehirn 2021 online, the Annual Conference of the Fachgruppe Biologische Psychologie der DGPs and the DGPA. Although we miss meeting you in person, we believe that the online conference will be a great possibility to exchange ideas and meet friends and colleagues! You find more information here.
 

new paper: Cell-Type-Specific Dynamics of Calcium Activity in Cortical Circuits over the Course of Slow-Wave Sleep and Rapid Eye Movement Sleep

April, 8th 2021

There is a new paper by Niels Niethardt, Svenja B, and Jan Born published in The Journal of Neuroscience

PDF

DOI

October, 19th 2020

We have a new member in the lab: Svenja K has joined our team for her PhD

September, 17th 2020

Svenja will present her data on the role of sleep for the consolidation of rapidly acquired neocortical memories in the oral session “Learning and Memory” of this year’s ESRS conference. If you are attending, check it out!

July, 25th 2020

We have published a review on neocortical memory engrams with a focus on humans.

DOI

October, 9th 2019

Svenja Brodt has won the prestigious Attempto prize of the Tübingen neurosciences! Congratulations! (news link)

June, 20th 2019

Lea Himmer has won the prize of the section Biological Psychology of the German Psychological Society (DGPs) this year! Congratulations!

April, 24th 2019

Our new paper “Rehearsl initiates systems memory consolidation, sleep makes it last” was just published in Science Advances. Using fMRI, we show how rehearsal shifts mnemonic processing from the hippocampus to the posterior parietal cortex and how sleep stabilizes this transition.

November, 20th 2018

Our new paper “Fast track to the neocortex: A memory engram in posterior parietal cortex” was just published in Science. We show with diffusion-weighted MRI that plasticity develops rapidly – after just one learning session – for a declarative object-location task in the precuneus. This rapid plasticity drove correct memory recall; and it persisted for more than 12 h.